PFKM anticorps (Internal Region)

N° du produit ABIN6287047

Détail du produit anti-PFKM anticorps

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: PFKM is a protein encoded by the PKFM gene which is approximately 85,2 kDa. PFKM is localised to the cytoplasm. It is involved in glucose metabolism, carbon metabolism and AMP-activated protein kinase signalling. It exists as three isozymes which function as subunits of the mammalian tetramer phosphofructokinase. It catalyses the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. PFKM is expressed in the nervous system, muscle, heart, lung and kidney. Mutations in the PFKM gene may result in glycogen storage disease, mcardle disease and phosphoglycerate kinase deficiency. STJ95045 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PFKM protein.

Specificité: PFKM Polyclonal Antibody detects endogenous levels of PFKM protein.

Attributs du produit: Rabbit polyclonal to PFKM.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human PFKM.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur PFKM

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Autre désignation: PFKM (PFKM Produits)

Synonymes: anticorps GSD7, anticorps PFK-1, anticorps PFK1, anticorps PFKA, anticorps PFKX, anticorps AI131669, anticorps PFK-A, anticorps PFK-M, anticorps Pfk-4, anticorps Pfk4, anticorps Pfka, anticorps Pfkx, anticorps Pfk-M, anticorps M-PFK, anticorps PFKM, anticorps pfkm, anticorps zgc:92344, anticorps pfk, anticorps im:7137110, anticorps wu:fc58g11, anticorps phosphofructokinase, muscle, anticorps phosphofructokinase, platelet, anticorps phosphofructokinase, muscle a, anticorps phosphofructokinase, muscle S homeolog, anticorps phosphofructokinase, muscle b, anticorps PFKM, anticorps Pfkm, anticorps PFKP, anticorps pfkma, anticorps pfkm.S, anticorps pfkmb

Poids moléculaire: 85 kDa

ID gène: 5213

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg