Versican anticorps (N-Term)

N° du produit ABIN6287760

Détail du produit anti-Versican anticorps

Antigène: Versican (Vcan)

Épitope: AA 510-590, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Versican est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Versican is a protein encoded by the VCAN gene which is approximately 372,8 kDa. Versican is secreted into the extracellular space. It is involved in the integrin pathway, ERK signalling, glycosaminoglycan metabolism and phospholipase-C pathway. This protein falls under the aggrecan/versican proteoglycan family. It is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Versican is expressed in the cerebral white matter and plasma. Mutations in the VCAN gene may result in wagner vitreoretinopathy. STJ96239 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of versican protein.

Specificité: Versican Polyclonal Antibody detects endogenous levels of Versican protein.

Attributs du produit: Rabbit polyclonal to Versican.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Versican

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300
ELISA 1:10000

Commentaires:

Cerebral white matter and plasma. Isoform V0 and isoform V1 are expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas. Isoform V2 is restricted to normal brain and gliomas. Isoform V3 is found in all these tissues except medulloblastomas.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur Versican

Antigène: Versican (Vcan)

Autre désignation: Versican (Vcan Produits)

Synonymes: anticorps br146, anticorps cspg2, anticorps cspg2a, anticorps sb:cb63, anticorps versican, anticorps CSPG2, anticorps Cspg2, anticorps wgn, anticorps ervr, anticorps pg-m, anticorps wgn1, anticorps Xversican, anticorps dcan, anticorps cspg2b, anticorps fb99b07, anticorps wu:fb99b07, anticorps ERVR, anticorps GHAP, anticorps PG-M, anticorps WGN, anticorps WGN1, anticorps 5430420N07Rik, anticorps 9430051N09, anticorps DPEAAE, anticorps NG2, anticorps PG-M(V0), anticorps PG-M(V1), anticorps hdf, anticorps versican a, anticorps versican, anticorps versican b, anticorps vcana, anticorps VCAN, anticorps Vcan, anticorps vcan, anticorps vcanb

Poids moléculaire: 372.82 kDa

ID gène: 1462

UniProt: P13611

Pathways: Glycosaminoglycan Metabolic Process