MICU1 anticorps

N° du produit ABIN6288547

Détail du produit anti-MICU1 anticorps

Antigène: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MICU1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: MICU1 is a protein encoded by the MICU1 gene which is approximately 54,3 kDa. MICU1 is localised to the mitochondrion inner membrane and mitochondrion intermembrane space. It is involved in Ca, cAMP and lipid signalling and is an essential regulator of mitochondrial Ca2+ uptake under basal conditions. It interacts with a mitochondrial inner membrane Ca2+ channel and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. MICU1 is expressed in the nervous system, kidney, muscle, skin and thyroid. Mutations in the MICU1 gene may result in dermatitis. STJ97447 was developed from clone Mix and was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. The antibody detects endogenous MICU1 protein.

Specificité: The antibody detects endogenous MICU1 protein.

Attributs du produit: Mouse monoclonal to MICU1.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Immunogène: Recombinant Protein

Clone: Mix

Isotype: IgG1

Information d'application

Indications d'application: WB 1:1000-2000
IHC 1:100-200

Commentaires:

Expressed in epithelial cell lines. Strongly expressed in epidermal keratinocytes and dermal endothelial cells.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur MICU1

Antigène: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Autre désignation: MICU1 (MICU1 Produits)

Synonymes: anticorps CALC, anticorps CBARA1, anticorps EFHA3, anticorps C730016L05Rik, anticorps Calc, anticorps Cbara1, anticorps mitochondrial calcium uptake 1, anticorps MICU1, anticorps Micu1

ID gène: 10367

UniProt: Q9BPX6