BMF anticorps

N° du produit ABIN6290093

Détail du produit anti-BMF anticorps

Antigène: BMF (Bcl2 Modifying Factor (BMF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMF est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant protein of human BMF

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50 - 1:200

Commentaires:

Isoform 1 is mainly expressed in B-lymphoid cells, Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur BMF

Antigène: BMF (Bcl2 Modifying Factor (BMF))

Autre désignation: BMF (BMF Produits)

Synonymes: anticorps BMF, anticorps AW260063, anticorps AW411872, anticorps Bcl2 modifying factor, anticorps Bcl2 modifying factor L homeolog, anticorps BCL2 modifying factor, anticorps BMF, anticorps bmf.L, anticorps Bmf

Sujet: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti-or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 20.508 kDa

ID gène: 90427

UniProt: Q96LC9