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CAPN10 anticorps

CAPN10 Reactivité: Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6290136
  • Antigène Voir toutes CAPN10 Anticorps
    CAPN10 (Calpain 10 (CAPN10))
    Reactivité
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 19
    Lapin
    Clonalité
    • 19
    Polyclonal
    Conjugué
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CAPN10 est non-conjugé
    Application
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human CAPN10
    Isotype
    IgG
    Top Product
    Discover our top product CAPN10 Anticorps primaire
  • Indications d'application
    WB 1:500 - 1:2000
    Commentaires

    Detected in primary skeletal muscle cells (at protein level), Ubiquitous

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20C. Avoid freeze / thaw cycles.
  • Antigène
    CAPN10 (Calpain 10 (CAPN10))
    Autre désignation
    CAPN10 (CAPN10 Produits)
    Synonymes
    anticorps CAPN10, anticorps CANP10, anticorps NIDDM1, anticorps AW049679, anticorps Capn8, anticorps mKIAA1845, anticorps calpain 10, anticorps calpain 10 L homeolog, anticorps CAPN10, anticorps capn10.L, anticorps capn10, anticorps Capn10
    Sujet
    Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.
    Poids moléculaire
    74.952 kDa
    ID gène
    11132
    UniProt
    Q9HC96
    Pathways
    Positive Regulation of Peptide Hormone Secretion
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