PGK1 anticorps

N° du produit ABIN6290734

Détail du produit anti-PGK1 anticorps

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant protein of human PGK1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Commentaires:

Mainly expressed in spermatogonia, Localized on the principle piece in the sperm (at protein level), Expression significantly decreased in the testis of elderly men

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur PGK1

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Autre désignation: PGK1 (PGK1 Produits)

Synonymes: anticorps MIG10, anticorps PGKA, anticorps Pgk-1, anticorps Pgk, anticorps PGK, anticorps wu:fd59b07, anticorps wu:fj36g06, anticorps zgc:56252, anticorps zgc:77899, anticorps PGK1, anticorps phosphoglycerate kinase 1, anticorps pgk2, anticorps pgka, anticorps phosphoglycerate kinase 1, anticorps phosphoglycerate kinase 1 L homeolog, anticorps PGK1, anticorps Pgk1, anticorps pgk1, anticorps LOC100348124, anticorps pgk1.L

Sujet: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.

Poids moléculaire: 44.615 kDa

ID gène: 5230

UniProt: P00558

Pathways: Cellular Glucan Metabolic Process