CREB3 anticorps

N° du produit ABIN6291021

Détail du produit anti-CREB3 anticorps

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREB3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant protein of human CREB3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Commentaires:

Expressed in dendritic cells (DC), Weakly expressed in monocytes (at protein level), Ubiquitous

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur CREB3

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Autre désignation: CREB3 (CREB3 Produits)

Synonymes: anticorps LUMAN, anticorps LZIP, anticorps AU044960, anticorps AW538053, anticorps C80076, anticorps LZIP-1, anticorps LZIP-2, anticorps Luman, anticorps creb3, anticorps luman, anticorps lzip, anticorps cAMP responsive element binding protein 3, anticorps cAMP responsive element binding protein 3 S homeolog, anticorps CREB3, anticorps Creb3, anticorps creb3.S

Sujet: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.

Poids moléculaire: 43.917 kDa

ID gène: 10488

UniProt: O43889

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response