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S100A12 anticorps

S100A12 Reactivité: Humain IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6291358
  • Antigène Voir toutes S100A12 Anticorps
    S100A12 (S100 Calcium Binding Protein A12 (S100A12))
    Reactivité
    • 35
    • 10
    • 9
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 23
    • 12
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 26
    • 12
    Polyclonal
    Conjugué
    • 26
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp S100A12 est non-conjugé
    Application
    • 22
    • 19
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human S100A12
    Isotype
    IgG
    Top Product
    Discover our top product S100A12 Anticorps primaire
  • Indications d'application
    IHC 1:50 - 1:100
    Commentaires

    Predominantly expressed by neutrophils, monocytes and activated macrophages, Expressed by eosinophils and macrophages in asthmatic airways in regions where mast cells accumulate, Found in high concentrations in the serum of patients suffering from various inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and Kawasaki disease

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20C. Avoid freeze / thaw cycles.
  • Antigène
    S100A12 (S100 Calcium Binding Protein A12 (S100A12))
    Autre désignation
    S100A12 (S100A12 Produits)
    Synonymes
    anticorps CAAF1, anticorps CAGC, anticorps CGRP, anticorps ENRAGE, anticorps MRP-6, anticorps MRP6, anticorps p6, anticorps CO-AG, anticorps EN-RAGE, anticorps S100 calcium binding protein A12, anticorps protein S100-A12, anticorps S100A12, anticorps LOC101103771
    Sujet
    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
    Poids moléculaire
    10.575 kDa
    ID gène
    6283
    UniProt
    P80511
    Pathways
    Toll-Like Receptors Cascades, S100 Proteins
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