S100A12 anticorps
-
- Antigène Voir toutes S100A12 Anticorps
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp S100A12 est non-conjugé
-
Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human S100A12
- Isotype
- IgG
- Top Product
- Discover our top product S100A12 Anticorps primaire
-
-
- Indications d'application
- IHC 1:50 - 1:100
- Commentaires
-
Predominantly expressed by neutrophils, monocytes and activated macrophages, Expressed by eosinophils and macrophages in asthmatic airways in regions where mast cells accumulate, Found in high concentrations in the serum of patients suffering from various inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and Kawasaki disease
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
-
- Antigène
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
- Autre désignation
- S100A12 (S100A12 Produits)
- Synonymes
- anticorps CAAF1, anticorps CAGC, anticorps CGRP, anticorps ENRAGE, anticorps MRP-6, anticorps MRP6, anticorps p6, anticorps CO-AG, anticorps EN-RAGE, anticorps S100 calcium binding protein A12, anticorps protein S100-A12, anticorps S100A12, anticorps LOC101103771
- Sujet
- The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
- Poids moléculaire
- 10.575 kDa
- ID gène
- 6283
- UniProt
- P80511
- Pathways
- Toll-Like Receptors Cascades, S100 Proteins
-