BCAM anticorps

N° du produit ABIN6291879

Détail du produit anti-BCAM anticorps

Antigène: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAM est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic peptide of human BCAM

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Wide tissue distribution (highest in the pancreas and very low in brain), Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur BCAM

Antigène: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Autre désignation: BCAM (BCAM Produits)

Synonymes: anticorps cd239, anticorps msk19, anticorps MGC81012, anticorps LU, anticorps prr2, anticorps zgc:154034, anticorps 1200005K12Rik, anticorps B-CAM, anticorps Gplu, anticorps Lu, anticorps AU, anticorps CD239, anticorps MSK19, anticorps basal cell adhesion molecule (Lutheran blood group), anticorps basal cell adhesion molecule (Lutheran blood group) L homeolog, anticorps basal cell adhesion molecule, anticorps bcam, anticorps bcam.L, anticorps BCAM, anticorps Bcam

Sujet: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 67.405 kDa

ID gène: 4059

UniProt: P50895