HMGCS2 anticorps

N° du produit ABIN6292123

Détail du produit anti-HMGCS2 anticorps

Antigène: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGCS2 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human HMGCS2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Expression in liver is 200-fold higher than in any other tissue, Low expression in colon, kidney, testis, and pancreas, Very low expression in heart and skeletal muscle, Not detected in brain, The relative expression of isoform 3 (at mRNA level) is highest in heart (70%) and skeletal muscle (60%)

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur HMGCS2

Antigène: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Autre désignation: HMGCS2 (HMGCS2 Produits)

Synonymes: anticorps 1300002P16, anticorps mHS, anticorps DDBDRAFT_0219349, anticorps DDBDRAFT_0219924, anticorps DDB_0219349, anticorps DDB_0219924, anticorps Hmgcs1, anticorps Mt3h3mg, anticorps hmgCoA, anticorps 3-hydroxy-3-methylglutaryl-CoA synthase 2, anticorps 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2, anticorps hydroxymethylglutaryl-CoA synthase, anticorps hydroxymethylglutaryl-coa synthase, anticorps 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2, anticorps HMGCS2, anticorps Hmgcs2, anticorps mvaS, anticorps CNC05080, anticorps HMCS1, anticorps hgsA, anticorps MFER_RS00425, anticorps LOC100285783, anticorps ECU10_0510, anticorps Eint_100450

Sujet: The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 56.635 kDa

ID gène: 3158

UniProt: P54868

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha