PDGFC anticorps

N° du produit ABIN6292249

Détail du produit anti-PDGFC anticorps

Antigène: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFC est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human PDGFC

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Expressed in the fallopian tube, vascular smooth muscle cells in kidney, breast and colon and in visceral smooth muscle of the gastrointestinal tract, Highly expressed in retinal pigment epithelia, Expressed in medulloblastoma, In the kidney, constitutively expressed in parietal epithelial cells of Bowman's capsule, tubular epithelial cells and in arterial endothelial cells (at protein level), Highly expressed in the platelets, prostate, testis and uterus, Higher expression is observed in uterine leiomyomata, Weaker expression in the spleen, thymus, heart, pancreas, liver, ovary cells and small intestine, and negligible expression in the colon and peripheral blood leukocytes

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur PDGFC

Antigène: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Autre désignation: PDGFC (PDGFC Produits)

Synonymes: anticorps SCDGF, anticorps FALLOTEIN, anticorps 1110064L01Rik, anticorps AI647969, anticorps PDGF-C, anticorps platelet derived growth factor C, anticorps platelet-derived growth factor, C polypeptide, anticorps PDGFC, anticorps Pdgfc

Classe de substances: Viral Protein

Sujet: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 39.029 kDa

ID gène: 56034

UniProt: Q9NRA1

Pathways: Signalisation RTK, Platelet-derived growth Factor Receptor Signaling