TCIRG1 anticorps
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- Antigène Voir toutes TCIRG1 Anticorps
- TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TCIRG1 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human TCIRG1
- Isotype
- IgG
- Top Product
- Discover our top product TCIRG1 Anticorps primaire
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- Indications d'application
- WB 1:200 - 1:2000
- Commentaires
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Isoform long is highly expressed in osteoclastomas, Isoform short is highly expressed in thymus
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- Antigène
- TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))
- Autre désignation
- TCIRG1 (TCIRG1 Produits)
- Synonymes
- anticorps OC116, anticorps TIRC7, anticorps ATP6N1C, anticorps ATP6a3, anticorps Atp6i, anticorps OC-116, anticorps OPTB1, anticorps Stv1, anticorps Vph1, anticorps oc, anticorps ATP6V0A3, anticorps OC-116kDa, anticorps a3, anticorps T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3, anticorps T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3, anticorps T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3, anticorps Tcirg1, anticorps TCIRG1
- Sujet
- This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.
- Poids moléculaire
- 92.968 kDa
- ID gène
- 10312
- UniProt
- Q13488
- Pathways
- Transition Metal Ion Homeostasis, Proton Transport
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