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PCSK1 anticorps

PCSK1 Reactivité: Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6293443
  • Antigène Voir toutes PCSK1 Anticorps
    PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
    Reactivité
    • 18
    • 16
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Rat
    Hôte
    • 20
    • 6
    Lapin
    Clonalité
    • 20
    • 6
    Polyclonal
    Conjugué
    • 19
    • 3
    • 2
    • 2
    Cet anticorp PCSK1 est non-conjugé
    Application
    • 17
    • 14
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human PCSK1
    Isotype
    IgG
    Top Product
    Discover our top product PCSK1 Anticorps primaire
  • Indications d'application
    WB 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20C. Avoid freeze / thaw cycles.
  • Antigène
    PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
    Autre désignation
    PCSK1 (PCSK1 Produits)
    Synonymes
    anticorps BMIQ12, anticorps NEC1, anticorps PC1, anticorps PC3, anticorps SPC3, anticorps Nec-1, anticorps Nec1, anticorps Phpp-1, anticorps BDP, anticorps PC1/3, anticorps proprotein convertase subtilisin/kexin type 1, anticorps prohormone convertase 1, anticorps PCSK1, anticorps Pcsk1, anticorps pcsk1, anticorps PC1B
    Sujet
    This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene
    Poids moléculaire
    84.152 kDa
    ID gène
    5122
    UniProt
    P29120
    Pathways
    Peptide Hormone Metabolism
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