RASGRP2 anticorps

N° du produit ABIN6293518

Détail du produit anti-RASGRP2 anticorps

Antigène: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASGRP2 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human RASGRP2

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:2000

Commentaires:

Detected in platelets, neutrophils and T lymphocytes (at protein level), Expressed in brain where it is enriched in the striatum, Also expressed in the hematopoietic system, Detected in heart, brain, lung, placenta, liver, skeletal muscle and kidney

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur RASGRP2

Antigène: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Autre désignation: RASGRP2 (RASGRP2 Produits)

Synonymes: anticorps CALDAG-GEFI, anticorps CDC25L, anticorps xrasgrp2, anticorps RASGRP2, anticorps Caldaggef1, anticorps CalDAG-GEFI, anticorps rasgrp2, anticorps RAS guanyl releasing protein 2, anticorps RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog, anticorps RAS, guanyl releasing protein 2, anticorps RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog, anticorps RASGRP2, anticorps rasgrp2.S, anticorps Rasgrp2, anticorps rasgrp2.L

Sujet: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

Poids moléculaire: 69.248 kDa

ID gène: 10235

UniProt: Q7LDG7

Pathways: TCR Signaling