SLIT2 anticorps

N° du produit ABIN6293578

Détail du produit anti-SLIT2 anticorps

Antigène: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLIT2 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human SLIT2

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:2000

Commentaires:

Fetal lung and kidney, and adult spinal cord, Weak expression in adult adrenal gland, thyroid, trachea and other tissues examined

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur SLIT2

Antigène: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Autre désignation: SLIT2 (SLIT2 Produits)

Synonymes: anticorps SLIL3, anticorps Slit-2, anticorps Drad-1, anticorps E030015M03Rik, anticorps E130320P19Rik, anticorps Slil3, anticorps mKIAA4141, anticorps Slit, anticorps slil3, anticorps slit-2, anticorps slit2-a, anticorps SLIT2, anticorps slit guidance ligand 2, anticorps slit homolog 2 (Drosophila), anticorps slit guidance ligand 2 S homeolog, anticorps SLIT2, anticorps Slit2, anticorps slit2, anticorps slit2.S

Sujet: This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 169.87 kDa

ID gène: 9353

UniProt: O94813

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration