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NR3C2 anticorps (Middle Region)

NR3C2 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN629576
  • Antigène Voir toutes NR3C2 Anticorps
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Épitope
    • 16
    • 15
    • 15
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 58
    • 46
    • 30
    • 17
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 71
    • 5
    Lapin
    Clonalité
    • 70
    • 6
    Polyclonal
    Conjugué
    • 28
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Cet anticorp NR3C2 est non-conjugé
    Application
    • 73
    • 39
    • 39
    • 20
    • 14
    • 12
    • 10
    • 9
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    NR3 C2 antibody was raised against the middle region of NR3 2
    Purification
    Purified
    Immunogène
    NR3 C2 antibody was raised using the middle region of NR3 2 corresponding to a region with amino acids RRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPP
    Top Product
    Discover our top product NR3C2 Anticorps primaire
  • Indications d'application
    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    NR3C2 Blocking Peptide, catalog no. 33R-8142, is also available for use as a blocking control in assays to test for specificity of this NR3C2 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NR0 2 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Autre désignation
    NR3C2 (NR3C2 Produits)
    Synonymes
    anticorps mr, anticorps si:ch211-189l17.1, anticorps LOC100302443, anticorps NR3C2, anticorps LOC443144, anticorps MLR, anticorps MR, anticorps MCR, anticorps NR3C2VIT, anticorps Mlr, anticorps mlr, anticorps nuclear receptor subfamily 3, group C, member 2, anticorps nuclear receptor subfamily 3 group C member 2, anticorps mineralocorticoid receptor, anticorps nuclear receptor subfamily 3 group C member 2 L homeolog, anticorps nr3c2, anticorps NR3C2, anticorps LOC443144, anticorps Nr3c2, anticorps nr3c2.L
    Sujet
    NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
    Poids moléculaire
    107 kDa (MW of target protein)
    Pathways
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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