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CD45 anticorps

PTPRC Reactivité: Humain FACS, IHC, IF Hôte: Souris Monoclonal unconjugated
N° du produit ABIN6297667
  • Antigène Voir toutes CD45 (PTPRC) Anticorps
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    Reactivité
    • 419
    • 252
    • 88
    • 29
    • 20
    • 16
    • 15
    • 10
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 305
    • 201
    • 148
    • 2
    • 1
    • 1
    Souris
    Clonalité
    • 513
    • 137
    • 1
    Monoclonal
    Conjugué
    • 185
    • 62
    • 54
    • 52
    • 39
    • 17
    • 15
    • 12
    • 12
    • 12
    • 10
    • 10
    • 10
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp CD45 est non-conjugé
    Application
    • 534
    • 213
    • 160
    • 137
    • 135
    • 80
    • 70
    • 60
    • 47
    • 27
    • 19
    • 17
    • 15
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    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Fonction
    Mouse anti-Human CD45RA Antibody [Sodium Azide Free]
    Specificité
    Cell surface
    Purification
    Stimulated human leukocytes were used as immunogen for this anti-CD45RA antibody.
    Immunogène
    Stimulated human leukocytes were used as immunogen for this anti-CD45RA antibody.
    Top Product
    Discover our top product PTPRC Anticorps primaire
  • Indications d'application
    Flow Cytometry: 0.5-1 μg/million cells
    Immunofluorescence: 1-2 μg/mL
    Immunohistology (FFPE): 0.5-1.0 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    Restrictions
    For Research Use only
  • Buffer
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    Agent conservateur
    Azide free
    Stock
    4 °C,-20 °C
    Stockage commentaire
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Antigène
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    Autre désignation
    Receptor-type tyrosine-protein phosphatase C (PTPRC Produits)
    Synonymes
    anticorps PTPRC, anticorps si:dkeyp-47c5.1, anticorps B220, anticorps CD45, anticorps CD45R, anticorps GP180, anticorps L-CA, anticorps LCA, anticorps LY5, anticorps T200, anticorps Cd45, anticorps Ly-5, anticorps Lyt-4, anticorps loc, anticorps Lca, anticorps RT7, anticorps cd45, anticorps protein tyrosine phosphatase, receptor type C, anticorps protein tyrosine phosphatase, receptor type, C, anticorps receptor-type tyrosine-protein phosphatase C, anticorps PTPRC, anticorps ptprc, anticorps LOC100074271, anticorps Ptprc
    Sujet

    Target Description: CD45RA is an isoform of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. CD45RA is expressed on 40-50 % of peripheral CD4+ T-cells, 50 % of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells.

    Gene Symbol: PTPRC///CD45

    ID gène
    5788
    UniProt
    P08575
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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