RNMT anticorps

N° du produit ABIN6297753

Détail du produit anti-RNMT anticorps

Antigène: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Reactivité: Humain, Rat, Boeuf (Vache), Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RNMT est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Fonction: Mouse anti-Human/Cow/Dog/Rat TAG-72 Antibody Cocktail [Sodium Azide Free]

Specificité: Cytoplasmic and cell surface

Purification: The membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and TAG-72 protein (CA72/733) were used as the immunogens for this antibody cocktail.

Immunogène: The membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and TAG-72 protein (CA72/733) were used as the immunogens for this antibody cocktail.

Information d'application

Indications d'application: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur RNMT

Antigène: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Autre désignation: mRNA cap guanine-N7 methyltransferase   (RNMT Produits)

Synonymes: anticorps xCMT1, anticorps MET, anticorps RG7MT1, anticorps hCMT1c, anticorps 2610002P10Rik, anticorps AI848273, anticorps Rg7mt1, anticorps mKIAA0398, anticorps rnmt, anticorps im:6910566, anticorps wu:fi09c12, anticorps RNA (guanine-7-) methyltransferase L homeolog, anticorps RNA guanine-7 methyltransferase, anticorps RNA (guanine-7-) methyltransferase, anticorps rnmt.L, anticorps RNMT, anticorps Rnmt, anticorps rnmt

Sujet:

Target Description: This antibody recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 antibody with a GCDFP-15 antibody is valuable in the diagnosis of apocrine carcinoma.

Gene Symbol: tag-72  C25A1.3

ID gène: 182875

UniProt: Q9XVS1