HLA-DQA1 anticorps
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- Antigène Voir toutes HLA-DQA1 Anticorps
- HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1))
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Reactivité
- Humain, Porc
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp HLA-DQA1 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Fonction
- Mouse anti-Human/Pig HLA-DQ Antibody (MHC II) [Sodium Azide Free]
- Specificité
- Cell surface
- Purification
- The T4-positive CTL clone HG-38 was used as the immunogen for the HLA-DQ antibody.
- Immunogène
- The T4-positive CTL clone HG-38 was used as the immunogen for the HLA-DQ antibody.
- Top Product
- Discover our top product HLA-DQA1 Anticorps primaire
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- Indications d'application
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT (1) - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Agent conservateur
- Azide free
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Antigène
- HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1))
- Autre désignation
- HLA class II histocompatibility antigen, DQ alpha 1 chain (HLA-DQA1 Produits)
- Synonymes
- anticorps CD, anticorps CELIAC1, anticorps DQ-A1, anticorps GSE, anticorps HLA-DQA, anticorps BoLA-DQA, anticorps hla-dqa1, anticorps major histocompatibility complex, class II, DQ alpha 1, anticorps major histocompatibility complex, class II, DQ alpha, type 1, anticorps major histocompatibility complex, class II, DQ alpha 1 L homeolog, anticorps HLA-DQA1, anticorps BOLA-DQA1, anticorps hla-dqa1.L
- Sujet
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Target Description: Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
Gene Symbol: HLA-DQA1///HLA-DQB1///HLA-DQB
- UniProt
- P01909, P01920
- Pathways
- TCR Signaling, Cancer Immune Checkpoints
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