STAT6 anticorps (Biotin)
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- Antigène Voir toutes STAT6 Anticorps
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp STAT6 est conjugé à/à la Biotin
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Application
- ELISA
- Fonction
- Rabbit anti-Human Phosphorylated STAT6 Antibody [+Biotin],
- Immunogène
- This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen. The IgG fraction was purified by Protein A affinity chromatography.
- Top Product
- Discover our top product STAT6 Anticorps primaire
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- Indications d'application
- ELISA (recommended work dilution= 1:8,000)
- Restrictions
- For Research Use only
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- Reconstitution
- Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution . Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- -20°C
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- Antigène
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
- Autre désignation
- Signal transducer and activator of transcription 6 (STAT6 Produits)
- Synonymes
- anticorps D12S1644, anticorps IL-4-STAT, anticorps STAT6B, anticorps STAT6C, anticorps signal transducer and activator of transcription 6, anticorps signal transducer and activator of transcription 6-like, anticorps STAT6, anticorps Stat6, anticorps LOC100859543
- Sujet
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Target Description: STAT6 is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors.In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.Phospho-STAT6-PY is the phosphorylated form of STAT6 protein.
Gene Symbol: STAT6
- ID gène
- 6778
- UniProt
- P42226
- Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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