PTP4A3 anticorps

N° du produit ABIN6297877

Détail du produit anti-PTP4A3 anticorps

Antigène: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTP4A3 est non-conjugé

Application: Veuillez nous consulter SVP

Fonction: Rabbit Anti-PRL3 Antibody

Immunogène: This PRL3 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human PRL3.

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PTP4A3

Antigène: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Autre désignation: PRL3 (PTP4A3 Produits)

Synonymes: anticorps PRL-3, anticorps PRL-R, anticorps PRL3, anticorps wu:fc54b05, anticorps wu:fv52d11, anticorps zgc:77109, anticorps prl-3, anticorps prl3, anticorps ptpcaax3, anticorps PTP4A3, anticorps AV088979, anticorps Prl-3, anticorps pPtp4a3, anticorps protein tyrosine phosphatase type IVA, member 3, anticorps protein tyrosine phosphatase type IVA, member 3 L homeolog, anticorps protein tyrosine phosphatase 4a3, anticorps PTP4A3, anticorps ptp4a3, anticorps ptp4a3.L, anticorps Ptp4a3

Sujet:

Target Description: The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. PRL-3 expression was found to be up-regulated in human liver carcinoma compared with normal liver. Its expression in colorectal cancers may contribute to the establishment of liver metastasis. In a different study, PRL-3 is found to be expressed in tumor metastasis and vasculature, regardless of the tumor source.

Gene Symbol: PTP4A3

ID gène: 11156

UniProt: O75365