Ube2t anticorps

N° du produit ABIN6298352

Détail du produit anti-Ube2t anticorps

Antigène: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ube2t est non-conjugé

Application: Veuillez nous consulter SVP

Fonction: Rabbit Anti-UBE2T Antibody,

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur Ube2t

Antigène: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Autre désignation: UBE2T (Ube2t Produits)

Synonymes: anticorps PIG50, anticorps UBE2T, anticorps 2700084L22Rik, anticorps C80607, anticorps RGD1310816, anticorps hspc150, anticorps wu:fj86h11, anticorps zgc:153687, anticorps ubiquitin conjugating enzyme E2 T, anticorps ubiquitin-conjugating enzyme E2T, anticorps ubiquitin conjugating enzyme E2T S homeolog, anticorps ubiquitin-conjugating enzyme E2T (putative), anticorps UBE2T, anticorps Ube2t, anticorps ube2t.S, anticorps ube2t

Sujet:

Target Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.

Gene Symbol: UBE2T

ID gène: 29089

UniProt: Q9NPD8

Pathways: Chromatin Binding