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ADAMTS4 anticorps (N-Term)

ADAMTS4 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN630877
  • Antigène Voir toutes ADAMTS4 Anticorps
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    Épitope
    • 15
    • 12
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 81
    • 48
    • 20
    • 10
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 73
    • 10
    • 4
    Lapin
    Clonalité
    • 78
    • 9
    Polyclonal
    Conjugué
    • 41
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADAMTS4 est non-conjugé
    Application
    • 64
    • 29
    • 15
    • 13
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    ADAMTS4 antibody was raised against the N terminal of ADAMTS4
    Purification
    Affinity purified
    Immunogène
    ADAMTS4 antibody was raised using the N terminal of ADAMTS4 corresponding to a region with amino acids GVQVEGLTVQYLGQAPELLGGAEPGTYLTGTINGDPESVASLHWDGGALL
    Top Product
    Discover our top product ADAMTS4 Anticorps primaire
  • Indications d'application
    WB: 0.5 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    ADAMTS4 Blocking Peptide, catalog no. 33R-3654, is also available for use as a blocking control in assays to test for specificity of this ADAMTS4 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ADAMTS4 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    Autre désignation
    ADAMTS4 (ADAMTS4 Produits)
    Synonymes
    anticorps 3830423K05, anticorps ADAM-TS4, anticorps ADAMTS-2, anticorps ADMP-1, anticorps mKIAA0688, anticorps ADAMTS-4, anticorps ADAMTS4, anticorps a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, anticorps ADAM metallopeptidase with thrombospondin type 1 motif 4, anticorps ADAM metallopeptidase with thrombospondin type 1 motif, 4, anticorps Adamts4, anticorps ADAMTS4
    Sujet
    ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
    Poids moléculaire
    37 kDa (MW of target protein)
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