CACNB4 anticorps (Middle Region)
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- Antigène Voir toutes CACNB4 Anticorps
- CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CACNB4 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- CACNB4 antibody was raised against the middle region of CACNB4
- Purification
- Affinity purified
- Immunogène
- CACNB4 antibody was raised using the middle region of CACNB4 corresponding to a region with amino acids GVPDPGTGASSGTRTPDVKAFLESPWSLDPASASPEPVPHILASSRQWDP
- Top Product
- Discover our top product CACNB4 Anticorps primaire
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- Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Commentaires
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CACNB4 Blocking Peptide, catalog no. 33R-3649, is also available for use as a blocking control in assays to test for specificity of this CACNB4 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CACNB4 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Antigène
- CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
- Autre désignation
- CACNB4 (CACNB4 Produits)
- Synonymes
- anticorps CAB4, anticorps CACNLB4, anticorps EA5, anticorps EIG9, anticorps EJM, anticorps EJM4, anticorps EJM6, anticorps 3110038O15Rik, anticorps Cchb4, anticorps lethargic, anticorps lh, anticorps CACNB4, anticorps cacnb4.2, anticorps calcium voltage-gated channel auxiliary subunit beta 4, anticorps calcium channel, voltage-dependent, beta 4 subunit, anticorps calcium channel, voltage-dependent, beta 4a subunit, anticorps CACNB4, anticorps Cacnb4, anticorps cacnb4.1, anticorps cacnb4, anticorps cacnb4a
- Sujet
- CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).
- Poids moléculaire
- 50 kDa (MW of target protein)
- Pathways
- cAMP Metabolic Process, Skeletal Muscle Fiber Development
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