NR4A2 anticorps

N° du produit ABIN636365

Détail du produit anti-NR4A2 anticorps

Antigène: NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR4A2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Souris, Rat (Rattus)

Purification: Affinity chromatography purified

Immunogène: Nurr1 antibody was raised in rabbit using a synthetic peptide comprising an internal sequence of the human Nurr1 protein as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:100-1:200, WB: 1:1,000-1:2,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Affinity purified and supplied in PBS, with 0.02 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur NR4A2

Antigène: NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))

Autre désignation: Nurr1 (NR4A2 Produits)

Synonymes: anticorps nr41/42/43, anticorps Nr4a2, anticorps nurr1, anticorps not, anticorps rnr1, anticorps hzf-3, anticorps tinur, anticorps NGFI-B, anticorps HZF-3, anticorps NOT, anticorps NURR1, anticorps RNR1, anticorps TINUR, anticorps Nurr1, anticorps RNR-1, anticorps TINOR, anticorps ngf1b, anticorps nr4a2, anticorps zgc:92696, anticorps nuclear receptor subfamily 4 group A member 2, anticorps nuclear receptor, anticorps nuclear receptor subfamily 4, group A, member 2, anticorps nuclear receptor subfamily 4, group A, member 2b, anticorps NR4A2, anticorps nr41/42/43, anticorps nr4a2, anticorps Nr4a2, anticorps nr4a2b

Sujet: The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of Mouse and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype.

Pathways: Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway