NLRP12 anticorps

N° du produit ABIN652311

Détail du produit anti-NLRP12 anticorps

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP12 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NLRP12 antibody is generated from rabbits immunized with human NLRP12 recombinant protein.

Clone: RB22861

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur NLRP12

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Autre désignation: NLRP12 (NLRP12 Produits)

Synonymes: anticorps Nalp12, anticorps NALP12, anticorps CLR19.3, anticorps FCAS2, anticorps PAN6, anticorps PYPAF7, anticorps RNO, anticorps RNO2, anticorps NLR family, pyrin domain containing 12, anticorps NLR family pyrin domain containing 12, anticorps NACHT, LRR and PYD domains-containing protein 3, anticorps Nlrp12, anticorps NLRP12, anticorps LOC100018508

Sujet: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes.

Poids moléculaire: 120173

ID gène: 91662

NCBI Accession: NP_001264055, NP_001264058, NP_653288

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome