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SLC8A1 anticorps (AA 296-325)

SLC8A1 Reactivité: Humain, Souris WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB21687 unconjugated
N° du produit ABIN652886
  • Antigène Voir toutes SLC8A1 Anticorps
    SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))
    Épitope
    • 16
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 296-325
    Reactivité
    • 34
    • 28
    • 27
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 36
    Lapin
    Clonalité
    • 36
    Polyclonal
    Conjugué
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLC8A1 est non-conjugé
    Application
    • 36
    • 18
    • 13
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This SLC8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human SLC8A1.
    Clone
    RB21687
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SLC8A1 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))
    Autre désignation
    SLC8A1 (SLC8A1 Produits)
    Synonymes
    anticorps NCX1, anticorps AI852629, anticorps AV344025, anticorps D930008O12Rik, anticorps Ncx1, anticorps Ncx, anticorps SLC8A1, anticorps ncx1n, anticorps solute carrier family 8 member A1, anticorps solute carrier family 8 (sodium/calcium exchanger), member 1, anticorps solute carrier family 8 (sodium/calcium exchanger), member 1b, anticorps sodium/calcium exchanger 1, anticorps SLC8A1, anticorps Slc8a1, anticorps slc8a1b, anticorps Tsp_07038
    Sujet
    In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) centration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.
    Poids moléculaire
    108547
    ID gène
    6546
    NCBI Accession
    NP_001106271, NP_001106272, NP_001106273, NP_001239553, NP_066920
    UniProt
    P32418
    Pathways
    Myometrial Relaxation and Contraction
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