DFFB anticorps (N-Term)

N° du produit ABIN653798

Détail du produit anti-DFFB anticorps

Antigène: DFFB (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))

Épitope: AA 1-30, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DFFB est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DFFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DFFB.

Clone: RB24419

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur DFFB

Antigène: DFFB (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))

Autre désignation: DFFB (DFFB Produits)

Synonymes: anticorps CAD, anticorps CPAN, anticorps DFF-40, anticorps DFF2, anticorps DFF40, anticorps LOC100223514, anticorps 40kDa, anticorps 5730477D02Rik, anticorps Didff, anticorps Cad, anticorps carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, anticorps DNA fragmentation factor subunit beta, anticorps DNA fragmentation factor, beta polypeptide (caspase-activated DNase), anticorps DNA fragmentation factor, beta subunit, anticorps CAD, anticorps DFFB, anticorps dffb, anticorps LOC100223514, anticorps Dffb

Sujet: Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis.

Poids moléculaire: 39110

ID gène: 1677

NCBI Accession: NP_004393

UniProt: O76075

Pathways: Apoptose, Caspase Cascade in Apoptosis