ADH4 anticorps (C-Term)

N° du produit ABIN654087

Détail du produit anti-ADH4 anticorps

Antigène: ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))

Épitope: AA 319-348, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADH4 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ADH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-348 amino acids from the C-terminal region of human ADH4.

Clone: RB21606

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ADH4 (ABIN654087)

Attignon, Leblanc, Le-Grand, Duval, Aggerbeck, Rouach, Blanc: "Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells." dans: Archives of toxicology, Vol. 91, Issue 1, pp. 313-324, (2017) (PubMed).

Renon, Legrand, Blanc, Daubigney, Bokobza, Mortreux, Paul, Delabar, Rouach, Andreau, Janel: "Impact of Dyrk1A level on alcohol metabolism." dans: Biochimica et biophysica acta, Vol. 1862, Issue 9, pp. 1495-503, (2016) (PubMed).

Détails sur ADH4

Antigène: ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))

Autre désignation: ADH4 (ADH4 Produits)

Synonymes: anticorps ADH-2, anticorps Adh2, anticorps ADH-1, anticorps Ac1002, anticorps alcohol dehydrogenase 4 (class II), pi polypeptide, anticorps alcohol dehydrogenase Adh4, anticorps ADH4, anticorps adh4, anticorps Adh4

Sujet: This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.

Poids moléculaire: 40222

ID gène: 127

NCBI Accession: NP_000661

UniProt: P08319

Pathways: Transition Metal Ion Homeostasis