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CYP1A2 anticorps (AA 255-282)

CYP1A2 Reactivité: Humain, Souris WB, IF, IHC (p) Hôte: Lapin Polyclonal RB16939 unconjugated
N° du produit ABIN655272
  • Antigène Voir toutes CYP1A2 Anticorps
    CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))
    Épitope
    • 16
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 255-282
    Reactivité
    • 63
    • 29
    • 23
    Humain, Souris
    Hôte
    • 51
    • 13
    • 2
    Lapin
    Clonalité
    • 54
    • 12
    Polyclonal
    Conjugué
    • 35
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CYP1A2 est non-conjugé
    Application
    • 56
    • 33
    • 23
    • 17
    • 17
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This CYP1A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from the Central region of human CYP1A2.
    Clone
    RB16939
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CYP1A2 Anticorps primaire
  • Indications d'application
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Sriwattanapong, Slocum, Chawanthayatham, Fedeles, Egner, Groopman, Satayavivad, Croy, Essigmann: "Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 160, Issue 1, pp. 173-179, (2018) (PubMed).

    Okamatsu, Kawakami, Komatsu, Kitazawa, Uno, Teraoka: "Functional expression and comparative characterization of four feline P450 cytochromes using fluorescent substrates." dans: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 47, Issue 11, pp. 951-961, (2017) (PubMed).

  • Antigène
    CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))
    Autre désignation
    CYP1A2 (CYP1A2 Produits)
    Synonymes
    anticorps CP12, anticorps P3-450, anticorps P450(PA), anticorps CYP1A2, anticorps CYPIA2, anticorps P450-PM4, anticorps Cyp1a1, anticorps P450-3, anticorps CYPD45, anticorps P-450d, anticorps RATCYPD45, anticorps CYP1A5, anticorps CP450, anticorps CYP-IA2, anticorps cytochrome P450 family 1 subfamily A member 2, anticorps cytochrome P450 1A2, anticorps cytochrome P450 LM4, anticorps cytochrome P450, family 1, subfamily A, polypeptide 2, anticorps cytochrome P450, family 1, subfamily a, polypeptide 2, anticorps cytochrome P450 1A2-like, anticorps CYP1A2, anticorps LOC100328937, anticorps Cyp1a2, anticorps VDBG_06455, anticorps LOC101825565, anticorps LOC102130662
    Sujet
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.
    Poids moléculaire
    58407
    ID gène
    1544
    NCBI Accession
    NP_000752
    UniProt
    P05177
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