RFWD2 anticorps (N-Term)

N° du produit ABIN655275

Détail du produit anti-RFWD2 anticorps

Antigène: RFWD2 (Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))

Épitope: AA 37-65, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFWD2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This COP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human COP1.

Clone: RB19572

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur RFWD2

Antigène: RFWD2 (Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))

Autre désignation: COP1 (RFWD2 Produits)

Synonymes: anticorps COP1, anticorps RNF200, anticorps AI316802, anticorps C80879, anticorps Cop1, anticorps RGD1304773, anticorps RFWD2, anticorps cop1, anticorps rnf200, anticorps zgc:163067, anticorps ring finger and WD repeat domain 2, anticorps ring finger and WD repeat domain 2, E3 ubiquitin protein ligase, anticorps ring finger and WD repeat domain 2, E3 ubiquitin protein ligase L homeolog, anticorps RFWD2, anticorps Rfwd2, anticorps rfwd2, anticorps rfwd2.L

Sujet: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

Poids moléculaire: 22625

ID gène: 114769

NCBI Accession: NP_001017534, NP_443121

UniProt: Q5EG05

Pathways: Photoperiodism