This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This POLR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human POLR1B.
anticorps RPOL-1l, anticorps MGC68946, anticorps 128kDa, anticorps D630020H17Rik, anticorps RPA116, anticorps RPA135, anticorps RPA2, anticorps Rpo1-2, anticorps RNA polymerase I subunit B, anticorps polymerase (RNA) I polypeptide B L homeolog, anticorps polymerase (RNA) I polypeptide B, 128kDa, anticorps polymerase (RNA) I polypeptide B, anticorps DNA-directed RNA polymerase I subunit RPA2, anticorps POLR1B, anticorps polr1b.L, anticorps polr1b, anticorps LOC100563266, anticorps LOC100634236, anticorps Polr1b
Sujet
Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).