DYRK1A anticorps
-
- Antigène Voir toutes DYRK1A Anticorps
- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp DYRK1A est non-conjugé
-
Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human DYRK1A
- Isotype
- IgG
- Top Product
- Discover our top product DYRK1A Anticorps primaire
-
-
- Indications d'application
- WB 1:500 - 1:1000
- Restrictions
- For Research Use only
-
- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
- Autre désignation
- DYRK1A (DYRK1A Produits)
- Synonymes
- anticorps DYRK1A, anticorps dyrk, anticorps dyrk1, anticorps hp86, anticorps mnb, anticorps mnbh, anticorps DYRK, anticorps DYRK1, anticorps HP86, anticorps MNB, anticorps MNBH, anticorps MRD7, anticorps 2310043O08Rik, anticorps D16Ertd272e, anticorps D16Ertd493e, anticorps Dyrk, anticorps ENSMUSG00000074897, anticorps Gm10783, anticorps Mnbh, anticorps Mp86, anticorps mmb, anticorps PSK47, anticorps dual specificity tyrosine phosphorylation regulated kinase 1A, anticorps dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, anticorps dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a, anticorps dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog, anticorps DYRK1A, anticorps dyrk1a, anticorps Dyrk1a, anticorps dyrk1a.S
- Sujet
-
Synonyms: Dual specificity tyrosine phosphorylation regulated kinase,Dual specificity tyrosine (Y) phosphorylation regulated kinase 1A,Dual specificity tyrosine phosphorylation regulated kinase 1,Dual specificity tyrosine phosphorylation regulated kinase 1A,Dual specificity tyrosine-phosphorylation-regulated kinase 1A,Dual specificity YAK 1 related kinase,Dual specificity YAK1 related kinase,Dual specificity YAK1-related kinase,DYR1A,DYRK 1,DYRK 1A,DYRK,DYRK1,Dyrk1a,DYRKA,hMNB,HP 86,HP86,Minibrain (Drosophila) homolog,Minibrain homolog,Minibrain,Drosophila,homolog of,MNB,MNB protein kinase,Mnb protein kinase homolog hp86,MNB protein kinase,Serine/threonine-specific,MNB/DYRK protein kinase,MNBH,MRD7,OTTHUMP00000109090,OTTHUMP00000109091,OTTHUMP00000109094,OTTHUMP00000174799,Protein kinase minibrain homolog,Serine/threonine kinase MNB
Background: This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.
- Poids moléculaire
-
Observed_MW: 72kDa
Calculated_MW: 60kDa/61kDa/66kDa/84kDa/85kDa
- ID gène
- 1859
- UniProt
- Q13627
- Pathways
- Mitotic G1-G1/S Phases
-