SMARCA4 anticorps
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- Antigène Voir toutes SMARCA4 Anticorps
- SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SMARCA4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide of human SMARCA4
- Isotype
- IgG
- Top Product
- Discover our top product SMARCA4 Anticorps primaire
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- Indications d'application
- WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:20 - 1:50
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
- Autre désignation
- SMARCA4 (SMARCA4 Produits)
- Synonymes
- anticorps SMARCA4, anticorps BAF190, anticorps BAF190A, anticorps BRG1, anticorps MRD16, anticorps RTPS2, anticorps SNF2, anticorps SNF2L4, anticorps SNF2LB, anticorps SWI2, anticorps hSNF2b, anticorps brg-1, anticorps Brg1, anticorps HP1-BP72, anticorps SNF2beta, anticorps SW1/SNF, anticorps b2b692Clo, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, anticorps SMARCA4, anticorps Smarca4
- Sujet
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Synonyms: ATP dependent helicase SMARCA4,ATP-dependent helicase SMARCA4,BAF 190,BAF190,BAF190A,Brahma protein like 1,BRG1,BRG1 associated factor 190A,BRG1 protein,BRG1-associated factor 190A,BRM/SWI2 related gene 1,Global transcription activator homologous sequence,global transcription activator snf2l4,Homeotic gene regulator,hSNF2b,Mitotic growth and transcription activator,MRD16,Nuclear protein GRB1,Protein brahma homolog 1,Protein BRG-1,Protein BRG1,RTPS2,SMARC A4,SMARCA4,SMCA4,SNF2,SNF2 beta,SNF2 like 4,SNF2-beta,SNF2B,SNF2L4,SNF2LB,Sucrose nonfermenting like 4,SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4,SWI/SNF related,matrix associated,actin dependent regulator of chromatin,subfamily a,member 4,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4,SWI2,Transcription activator BRG1
Background: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
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Observed_MW: 180kDa
Calculated_MW: 181kDa/184kDa
- ID gène
- 6597
- UniProt
- P51532
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance
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