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GEN1 anticorps

GEN1 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6566734
  • Antigène Voir toutes GEN1 Anticorps
    GEN1 (Gen Endonuclease Homolog 1 (GEN1))
    Reactivité
    Humain, Souris
    Hôte
    • 30
    Lapin
    Clonalité
    • 30
    Polyclonal
    Conjugué
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GEN1 est non-conjugé
    Application
    • 30
    • 15
    • 13
    • 13
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human GEN1
    Isotype
    IgG
    Top Product
    Discover our top product GEN1 Anticorps primaire
  • Indications d'application
    WB 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    GEN1 (Gen Endonuclease Homolog 1 (GEN1))
    Autre désignation
    GEN1 (GEN1 Produits)
    Synonymes
    anticorps 5830483C08Rik, anticorps Gen, anticorps RGD1559792, anticorps GEN1, Holliday junction 5' flap endonuclease, anticorps GEN1 Holliday junction 5' flap endonuclease, anticorps GEN1, anticorps Gen1
    Sujet

    Synonyms: DKFZp781F0986,Flap endonuclease GEN homolog 1,FLJ40869,GEN 1,Gen,Gen homolog 1 endonuclease (Drosophila),Gen homolog 1 endonuclease,GEN,GEN1

    Background: This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.

    Poids moléculaire

    Observed_MW: 103kDa

    Calculated_MW: 102kDa

    ID gène
    348654
    UniProt
    Q17RS7
    Pathways
    Réparation de l'ADN
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