MYH11 anticorps

N° du produit ABIN6567033

Détail du produit anti-MYH11 anticorps

Antigène: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYH11 est non-conjugé

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MYH11 (NP_001035203.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MYH11

Antigène: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Autre désignation: MYH11 (MYH11 Produits)

Synonymes: anticorps AV071570, anticorps SM1, anticorps SM2, anticorps smMHC, anticorps AAT4, anticorps FAA4, anticorps SMHC, anticorps SMMHC, anticorps myosin, anticorps myh11, anticorps myosin, heavy polypeptide 11, smooth muscle, anticorps myosin heavy chain 11, anticorps myosin, heavy chain 11, smooth muscle, anticorps myosin, heavy chain 11a, smooth muscle, anticorps Myh11, anticorps MYH11, anticorps myh11a

Sujet: The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire:

Observed_MW: 250kDa

Calculated_MW: 223kDa/224kDa/227kDa/228kDa

ID gène: 4629

UniProt: P35749