SMAD1 anticorps

N° du produit ABIN6567043

Détail du produit anti-SMAD1 anticorps

Antigène: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant protein of human SMAD1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SMAD1

Antigène: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Autre désignation: SMAD1 (SMAD1 Produits)

Synonymes: anticorps MLP, anticorps Xmad1, anticorps Xsmad1, anticorps bsp1, anticorps jv4-1, anticorps jv41, anticorps madh1, anticorps madr1, anticorps smad-1, anticorps MADH1, anticorps fb39h09, anticorps wu:fb39h09, anticorps wu:fb97e04, anticorps 2/23, anticorps CG12399, anticorps Dmel\\CG12399, anticorps E(zen)2, anticorps En(vvl), anticorps MAD, anticorps Mat, anticorps P-Mad, anticorps P-mad, anticorps PMad, anticorps Smad, anticorps Smad1, anticorps apg, anticorps c28, anticorps dMAD, anticorps dMad, anticorps l(2)K00237, anticorps l(2)k00237, anticorps mad, anticorps p-Mad, anticorps pMAD, anticorps pMad, anticorps pSmad, anticorps BSP-1, anticorps BSP1, anticorps JV4-1, anticorps JV41, anticorps MADR1, anticorps AI528653, anticorps Madh1, anticorps Madr1, anticorps Mlp1, anticorps MusMLP, anticorps smad1, anticorps xmad, anticorps SMAD family member 1, anticorps Mothers against dpp, anticorps SMAD family member 1 L homeolog, anticorps smad1, anticorps SMAD1, anticorps Mad, anticorps Smad1, anticorps smad1.L

Sujet:

Synonyms: BSP-1,BSP1,HsMAD1,JV4-1,JV41,MAD homolog 1,MAD mothers against decapentaplegic homolog 1,Mad related protein 1,Mad-related protein 1,MADH1,MADR1,Mothers against decapentaplegic homolog 1,Mothers against DPP homolog 1,SMA- AND MAD-RELATED PROTEIN 1,SMAD 1,SMAD family member 1,SMAD mothers against DPP homolog 1,Smad1,SMAD1,TGF beta signaling protein 1,Transforming growth factor-beta-signaling protein 1

Background: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Poids moléculaire:

Observed_MW: 54kDa

Calculated_MW: 15kDa/52kDa

ID gène: 4086

UniProt: Q15797

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development