RENT2/UPF2 anticorps

N° du produit ABIN6567949

Détail du produit anti-RENT2/UPF2 anticorps

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RENT2/UPF2 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human UPF2 (NP_542166.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RENT2/UPF2

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Autre désignation: UPF2 (UPF2 Produits)

Synonymes: anticorps HUPF2, anticorps RENT2, anticorps smg-3, anticorps UPF2, regulator of nonsense mediated mRNA decay, anticorps UPF2 regulator of nonsense transcripts homolog (yeast), anticorps UPF2, anticorps Upf2, anticorps upf2

Sujet: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.

Poids moléculaire:

Observed_MW: 180kDa

Calculated_MW: 66kDa/147kDa

ID gène: 26019

UniProt: Q9HAU5