GSTM2 anticorps

N° du produit ABIN6568004

Détail du produit anti-GSTM2 anticorps

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human GSTM2 (NP_000839.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GSTM2

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Autre désignation: GSTM2 (GSTM2 Produits)

Synonymes: anticorps GSTA4, anticorps GST4, anticorps GSTM, anticorps GSTM2-2, anticorps GTHMUS, anticorps Gstb-2, anticorps Gstb2, anticorps GSTIV, anticorps glutathione S-transferase mu 2, anticorps glutathione S-transferase mu 2 (muscle), anticorps glutathione S-transferase Mu 2, anticorps glutathione S-transferase, mu 2, anticorps glutathione S-transferase 2, anticorps Glutathione S-transferase 4, anticorps Gstm2, anticorps GSTM2, anticorps LOC100732167, anticorps gst2, anticorps gst-4

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Poids moléculaire:

Observed_MW: 27kDa

Calculated_MW: 22kDa/25kDa

ID gène: 2946

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity