SSX2 anticorps

N° du produit ABIN6568037

Détail du produit anti-SSX2 anticorps

Antigène: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSX2 est non-conjugé

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human SSX2 (NP_783629.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SSX2

Antigène: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Autre désignation: SSX2 (SSX2 Produits)

Synonymes: anticorps CT5.2, anticorps CT5.2A, anticorps HD21, anticorps HOM-MEL-40, anticorps SSX, anticorps SSX2, anticorps SSX3, anticorps SSX family member 2, anticorps protein SSX2, anticorps synovial sarcoma, X breakpoint 2, anticorps SSX2, anticorps LOC741661, anticorps Ssx2

Sujet: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 21kDa/25kDa

ID gène: 6757

UniProt: Q16385