UIMC1 anticorps

N° du produit ABIN6568375

Détail du produit anti-UIMC1 anticorps

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UIMC1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human UIMC1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UIMC1

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Autre désignation: UIMC1 (UIMC1 Produits)

Synonymes: anticorps UIMC1, anticorps RAP80, anticorps X2HRIP110, anticorps 9430016E08Rik, anticorps D330018D10Rik, anticorps D630032M02Rik, anticorps RIP110, anticorps Rxrip110, anticorps RGD1307009, anticorps ubiquitin interaction motif containing 1, anticorps UIMC1, anticorps Uimc1

Sujet:

Synonyms: BRCA1-A complex subunit RAP80,Nuclear zinc finger protein RAP80,OTTHUMP00000161441,OTTHUMP00000223372,OTTHUMP00000223374,RAP80,Receptor associated protein 80,Receptor-associated protein 80,Retinoid X receptor interacting protein 110,Retinoid x receptor interacting protein,Retinoid X receptor-interacting protein 110,RIP110,Rxrip110,Ubiquitin interaction motif containing 1,Ubiquitin interaction motif containing protein 1,Ubiquitin interaction motif-containing protein 1,UIMC1,UIMC1,X2HRIP110

Background: This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 90kDa

Calculated_MW: 17kDa/38kDa/61kDa/70kDa/79kDa

ID gène: 51720

UniProt: Q96RL1

Pathways: Réparation de l'ADN, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus