BRE anticorps

N° du produit ABIN6568579

Détail du produit anti-BRE anticorps

Antigène: BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRE est non-conjugé

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human BRE (NP_954661.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BRE

Antigène: BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))

Autre désignation: BRE (BRE Produits)

Synonymes: anticorps brcc4, anticorps brcc45, anticorps BRE, anticorps LOC100231620, anticorps BRCC4, anticorps BRCC45, anticorps 6030405P19Rik, anticorps AI429776, anticorps B830038C02Rik, anticorps im:7141046, anticorps zgc:110368, anticorps BRISC and BRCA1 A complex member 2, anticorps brain and reproductive organ-expressed (TNFRSF1A modulator), anticorps BRISC and BRCA1 A complex member 2 L homeolog, anticorps babam2, anticorps BABAM2, anticorps Babam2, anticorps BRE, anticorps babam2.L

Sujet: This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.

Poids moléculaire:

Observed_MW: 44kDa

Calculated_MW: 42kDa/43kDa/46kDa

ID gène: 9577

UniProt: Q9NXR7

Pathways: Positive Regulation of Response to DNA Damage Stimulus