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CDK6 anticorps

CDK6 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6568709
  • Antigène Voir toutes CDK6 Anticorps
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    Reactivité
    • 127
    • 48
    • 25
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 110
    • 17
    Lapin
    Clonalité
    • 99
    • 28
    Polyclonal
    Conjugué
    • 68
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CDK6 est non-conjugé
    Application
    • 76
    • 38
    • 29
    • 27
    • 27
    • 24
    • 23
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human CDK6
    Isotype
    IgG
    Top Product
    Discover our top product CDK6 Anticorps primaire
  • Indications d'application
    WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    Autre désignation
    CDK6 (CDK6 Produits)
    Synonymes
    anticorps CDK6, anticorps PLSTIRE, anticorps 5830411I20, anticorps AI504062, anticorps Crk2, anticorps cyclin dependent kinase 6, anticorps cyclin-dependent kinase 6, anticorps CDK6, anticorps Cdk6
    Sujet

    Synonyms: CDK 6,CDK6,CDK6,Cell division protein kinase 6,Crk 2,Crk2,Cyclin dependent kinase 6,Cyclin-dependent kinase 6,MCPH12,MGC59692,p40,PLSTIRE,Serine/threonine protein kinase PLSTIRE,Serine/threonine-protein kinase PLSTIRE,STQTL11

    Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

    Poids moléculaire

    Observed_MW: 37kDa

    Calculated_MW: 36kDa

    ID gène
    1021
    UniProt
    Q00534
    Pathways
    Cycle Cellulaire, Mitotic G1-G1/S Phases
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