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KIR3DL1 anticorps

KIR3DL1 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6568803
  • Antigène Voir toutes KIR3DL1 Anticorps
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    Reactivité
    • 51
    • 18
    • 18
    • 1
    Humain, Souris
    Hôte
    • 46
    • 20
    Lapin
    Clonalité
    • 46
    • 20
    Polyclonal
    Conjugué
    • 27
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KIR3DL1 est non-conjugé
    Application
    • 47
    • 18
    • 18
    • 13
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human KIR3DL1 (NP_037421.2).
    Isotype
    IgG
    Top Product
    Discover our top product KIR3DL1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    Autre désignation
    KIR3DL1 (KIR3DL1 Produits)
    Synonymes
    anticorps KIR3DL1, anticorps KIR3DL3, anticorps CD158E1, anticorps KIR, anticorps KIR3DL1/S1, anticorps NKAT3, anticorps NKB1, anticorps NKB1B, anticorps Kirl1, anticorps Kirl2, anticorps Krl1, anticorps killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1, anticorps uncharacterized LOC100437736, anticorps killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1, anticorps KIR3DL1, anticorps LOC100437736, anticorps Kir3dl1
    Sujet
    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
    Poids moléculaire

    Observed_MW: 48kDa

    Calculated_MW: 38kDa/49kDa

    ID gène
    3811
    UniProt
    P43629
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