HSD11B1 anticorps

N° du produit ABIN6568805

Détail du produit anti-HSD11B1 anticorps

Antigène: HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD11B1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human HSD11B1 (NP_005516.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HSD11B1

Antigène: HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

Autre désignation: HSD11B1 (HSD11B1 Produits)

Synonymes: anticorps 11-DH, anticorps 11-beta-HSD1, anticorps CORTRD2, anticorps HDL, anticorps HSD11, anticorps HSD11B, anticorps HSD11L, anticorps SDR26C1, anticorps hsd11, anticorps hsd11b, anticorps LRRGT00065, anticorps hydroxysteroid 11-beta dehydrogenase 1, anticorps hydroxysteroid (11-beta) dehydrogenase 1b, anticorps hydroxysteroid (11-beta) dehydrogenase 1 L homeolog, anticorps HSD11B1, anticorps HSD11B1b, anticorps hsd11b1.L, anticorps Hsd11b1

Sujet: The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

Poids moléculaire:

Observed_MW: 32kDa

Calculated_MW: 32kDa

ID gène: 3290

UniProt: P28845

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process