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IDE anticorps

IDE Reactivité: Humain, Souris WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6568815
  • Antigène Voir toutes IDE Anticorps
    IDE (Insulin-Degrading Enzyme (IDE))
    Reactivité
    • 63
    • 27
    • 24
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 52
    • 10
    • 4
    Lapin
    Clonalité
    • 56
    • 10
    Polyclonal
    Conjugué
    • 37
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IDE est non-conjugé
    Application
    • 59
    • 27
    • 19
    • 14
    • 13
    • 12
    • 7
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human IDE
    Isotype
    IgG
    Top Product
    Discover our top product IDE Anticorps primaire
  • Indications d'application
    WB 1:500 - 1:2000 IF 1:10 - 1:100
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    IDE (Insulin-Degrading Enzyme (IDE))
    Autre désignation
    IDE (IDE Produits)
    Synonymes
    anticorps zgc:162603, anticorps IDE, anticorps 1300012G03Rik, anticorps 4833415K22Rik, anticorps AA675336, anticorps AI507533, anticorps INSDEGM, anticorps INSULYSIN, anticorps insulin degrading enzyme, anticorps insulin-degrading enzyme, anticorps metallopeptidase, anticorps IDE, anticorps ide, anticorps LOC591315, anticorps CC1G_01115, anticorps Bm1_26615, anticorps PTRG_10875, anticorps SJAG_01430, anticorps EBI_21700, anticorps VDBG_06702, anticorps LOAG_08082, anticorps PGTG_04982, anticorps Tsp_00424, anticorps Ide
    Sujet

    Synonyms: Abeta-degrading protease,FLJ35968,Ide,IDE,Insulin protease,Insulin-degrading enzyme,Insulinase,Insulysin,OTTHUMP00000020097

    Background: This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.

    Poids moléculaire

    Observed_MW: 118kDa

    Calculated_MW: 54kDa/117kDa

    ID gène
    3416
    UniProt
    P14735
    Pathways
    SARS-CoV-2 Protein Interactome
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