PTPN2 anticorps

N° du produit ABIN6568912

Détail du produit anti-PTPN2 anticorps

Antigène: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PTPN2 (NP_536348.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PTPN2

Antigène: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Autre désignation: PTPN2 (PTPN2 Produits)

Synonymes: anticorps PTN2, anticorps PTPT, anticorps TC-PTP, anticorps TCELLPTP, anticorps TCPTP, anticorps AI325124, anticorps Ptpt, anticorps PTP-1B, anticorps cb806, anticorps ptpn2, anticorps ptpn2l, anticorps wu:fc10h07, anticorps zgc:55339, anticorps zgc:76973, anticorps hm:zeh1546, anticorps zgc:63623, anticorps ptn2, anticorps ptpt, anticorps tc-ptp, anticorps tcellptp, anticorps tcptp, anticorps protein tyrosine phosphatase, non-receptor type 2, anticorps protein tyrosine phosphatase, non-receptor type 2 S homeolog, anticorps protein tyrosine phosphatase, non-receptor type 2, b, anticorps protein tyrosine phosphatase, non-receptor type 2, a, anticorps protein tyrosine phosphatase, non-receptor type 2 L homeolog, anticorps PTPN2, anticorps Ptpn2, anticorps ptpn2.S, anticorps ptpn2b, anticorps ptpn2a, anticorps ptpn2.L

Sujet: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.

Poids moléculaire:

Observed_MW: 45kDa

Calculated_MW: 40kDa/45kDa/48kDa

ID gène: 5771

UniProt: P17706

Pathways: EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling