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PTBP1 anticorps

PTBP1 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6568928
  • Antigène Voir toutes PTBP1 Anticorps
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    Reactivité
    • 64
    • 25
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 56
    • 7
    • 1
    Lapin
    Clonalité
    • 47
    • 17
    Polyclonal
    Conjugué
    • 30
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Cet anticorp PTBP1 est non-conjugé
    Application
    • 38
    • 24
    • 12
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human PTBP1 (NP_114368.1).
    Isotype
    IgG
    Top Product
    Discover our top product PTBP1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    Autre désignation
    PTBP1 (PTBP1 Produits)
    Synonymes
    anticorps HNRNP-I, anticorps HNRNPI, anticorps HNRPI, anticorps PTB, anticorps PTB-1, anticorps PTB-T, anticorps PTB2, anticorps PTB3, anticorps PTB4, anticorps pPTB, anticorps Ptb, anticorps hnrpi, anticorps hnrnp-I, anticorps vgrbp60, anticorps AA407203, anticorps AL033359, anticorps Pybp, anticorps Pybp1, anticorps Pybp2, anticorps ptbp1, anticorps wu:fb99f12, anticorps zgc:110689, anticorps ptb, anticorps ATPTB1, anticorps POLYPYRIMIDINE TRACT-BINDING, anticorps POLYPYRIMIDINE TRACT-BINDING PROTEIN 1, anticorps T4P13.16, anticorps T4P13_16, anticorps polypyrimidine tract-binding protein 1, anticorps PTBP1, anticorps polypyrimidine tract binding protein 1, anticorps polypyrimidine tract binding protein 1 S homeolog, anticorps polypyrimidine tract-binding protein, anticorps polypyrimidine tract binding protein 1a, anticorps polypyrimidine tract binding protein 1 L homeolog, anticorps polypyrimidine tract-binding protein 1, anticorps PTBP1, anticorps ptbp1.S, anticorps NAEGRDRAFT_80143, anticorps LOC100285404, anticorps Ptbp1, anticorps ptbp1a, anticorps ptbp1.L, anticorps PTB1, anticorps LOC100061673
    Sujet
    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.
    Poids moléculaire

    Observed_MW: 64kDa

    Calculated_MW: 57kDa/59kDa

    ID gène
    5725
    UniProt
    P26599
    Pathways
    Regulation of Muscle Cell Differentiation
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