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IL12RB1 anticorps

IL12RB1 Reactivité: Humain, Souris IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6568961
  • Antigène Voir toutes IL12RB1 Anticorps
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    Reactivité
    • 44
    • 25
    • 24
    Humain, Souris
    Hôte
    • 57
    • 7
    • 2
    • 1
    Lapin
    Clonalité
    • 60
    • 7
    Polyclonal
    Conjugué
    • 27
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL12RB1 est non-conjugé
    Application
    • 44
    • 13
    • 13
    • 12
    • 11
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human IL12RB1 (NP_714912.1).
    Isotype
    IgG
    Top Product
    Discover our top product IL12RB1 Anticorps primaire
  • Indications d'application
    IF 1:10-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    Autre désignation
    IL12RB1 (IL12RB1 Produits)
    Synonymes
    anticorps Il12rb, anticorps IL12RB1, anticorps IL-12R, anticorps CD212, anticorps IL-12R-BETA1, anticorps IL12RB, anticorps IL-12R[b], anticorps interleukin 12 receptor subunit beta 1, anticorps interleukin 12 receptor, beta 1, anticorps Il12rb1, anticorps IL12RB1
    Sujet
    The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
    Poids moléculaire

    Observed_MW: 73kDa

    Calculated_MW: 42kDa/72kDa/73kDa

    ID gène
    3594
    UniProt
    P42701
    Pathways
    Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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