SMARCA4 anticorps

N° du produit ABIN6569118

Détail du produit anti-SMARCA4 anticorps

Antigène: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMARCA4 est non-conjugé

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: A synthetic peptide of human SMARCA4 (NP_003063.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SMARCA4

Antigène: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Autre désignation: SMARCA4 (SMARCA4 Produits)

Synonymes: anticorps SMARCA4, anticorps BAF190, anticorps BAF190A, anticorps BRG1, anticorps MRD16, anticorps RTPS2, anticorps SNF2, anticorps SNF2L4, anticorps SNF2LB, anticorps SWI2, anticorps hSNF2b, anticorps brg-1, anticorps Brg1, anticorps HP1-BP72, anticorps SNF2beta, anticorps SW1/SNF, anticorps b2b692Clo, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, anticorps SMARCA4, anticorps Smarca4

Sujet: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 190kDa

Calculated_MW: 181kDa/184kDa

ID gène: 6597

UniProt: P51532

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance